When an ancient artifact awakens a fearsome spirit, the Ghostbusters must unite to save the world from an ice age and an army of the undead.

Maggie and Negan travel to post-apocalyptic Manhattan - long ago cut off from the mainland. The crumbling city is filled with the dead and denizens who have made it a world full of anarchy, danger, beauty, and terror.

When a single mom and her two kids arrive in a small town, they begin to discover their connection to the original Ghostbusters and the secret legacy their grandfather left behind.